<span style="font-size:14.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; color:black;mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language: HI" lang="EN-IN">Effect of methanolic leaf extract of <i>Cissampelos mucronata </i>A. Rich against indomethacin induced ulcer in rats</span>

181-183<span style="font-size:14.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:black;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">Five fractions (F1– F5) isolated from the methanolic leaf extract of Cissampelos mucronata; A. Rich were investigated for antiulcer activity. At the dose of 450 mg/kg, they showed varying degree of protection against ulcer induced by indomethacin; the order of protection being F1>F4>F5>F2>F3 The antiulcer potency of F1 and F2 is comparable with that of cimetidine(100 mg/kg, ip). Inhibition of gastric mucosal damage may partly contribute to the antiulcer activity of the fractions.